{"id":931,"date":"2023-02-21T17:58:12","date_gmt":"2023-02-21T17:58:12","guid":{"rendered":"https:\/\/study.research.sickkids.ca\/immunityseromark\/?page_id=931"},"modified":"2023-03-31T18:10:28","modified_gmt":"2023-03-31T18:10:28","slug":"seromark-vr","status":"publish","type":"page","link":"https:\/\/study.research.sickkids.ca\/immunityseromark\/seromark-vr\/","title":{"rendered":"Vaccine Response Study"},"content":{"rendered":"<p><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 fusion-flex-container hundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-right:0px;--awb-padding-left:0px;--awb-margin-bottom:0px;--awb-background-color:#ffffff;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-stretch fusion-flex-content-wrap\" style=\"width:calc( 100% + 0px ) !important;max-width:calc( 100% + 0px ) !important;margin-left: calc(-0px \/ 2 );margin-right: calc(-0px \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-padding-top:3%;--awb-padding-right:3%;--awb-padding-bottom:3%;--awb-padding-left:3%;--awb-bg-color:#ffffff;--awb-bg-color-hover:#ffffff;--awb-bg-size:cover;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:0px;--awb-margin-bottom-large:0px;--awb-spacing-left-large:0px;--awb-width-medium:50%;--awb-spacing-right-medium:0px;--awb-spacing-left-medium:0px;--awb-width-small:100%;--awb-spacing-right-small:0px;--awb-spacing-left-small:0px;\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-text fusion-text-1\"><h2>About the seroMARK-VR project<\/h2>\n<p><span style=\"font-size: 16px;\" data-fusion-font=\"true\">The <\/span><b style=\"font-size: 16px;\" data-fusion-font=\"true\">seroMARK Vaccine Response (seroMARK-VR) <\/b><span style=\"font-size: 16px;\" data-fusion-font=\"true\">project is a research study aiming to determine the immune response to COVID-19 vaccines amongst the Black Canadian population (African, Caribbean, North American) in comparison to other ethnic groups. Vaccine responses will be determined by measuring the immune response and presence of adverse events following <\/span><i><span style=\"font-size: 16px;\" data-fusion-font=\"true\">vaccination<\/span><\/i><span style=\"font-size: 16px;\" data-fusion-font=\"true\">. The project seeks to answer the following questions:<\/span><\/p>\n<ul>\n<li><span style=\"font-size: 16px;\" data-fusion-font=\"true\">What are the antibody responses to the COVID-19 vaccines among Black Canadians?<\/span><\/li>\n<li><span style=\"font-size: 16px;\" data-fusion-font=\"true\">To what extent of the population is vulnerable to infection and adverse outcomes?<\/span><\/li>\n<li><span style=\"font-size: 16px;\" data-fusion-font=\"true\">To what extent does the vaccine response provide sustained immunity to the virus over time?<\/span><\/li>\n<\/ul>\n<\/div><div class=\"fusion-content-boxes content-boxes columns row fusion-columns-1 fusion-columns-total-0 fusion-content-boxes-1 content-boxes-icon-with-title content-left\" style=\"--awb-hover-accent-color:#25afb4;--awb-circle-hover-accent-color:#25afb4;--awb-item-margin-bottom:40px;\" data-animationOffset=\"top-into-view\"><div class=\"fusion-clearfix\"><\/div><\/div><div class=\"fusion-builder-row fusion-builder-row-inner fusion-row fusion-flex-align-items-stretch fusion-flex-content-wrap\" style=\"--awb-flex-grow:0;--awb-flex-grow-medium:0;--awb-flex-grow-small:0;--awb-flex-shrink:0;--awb-flex-shrink-medium:0;--awb-flex-shrink-small:0;width:calc( 100% + 0px ) !important;max-width:calc( 100% + 0px ) !important;margin-left: calc(-0px \/ 2 );margin-right: calc(-0px \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-0 fusion_builder_column_inner_1_2 1_2 fusion-flex-column fusion-animated\" style=\"--awb-padding-top:3%;--awb-padding-right:3%;--awb-padding-bottom:3%;--awb-padding-left:3%;--awb-overflow:hidden;--awb-bg-color:#0046ad;--awb-bg-color-hover:#0046ad;--awb-bg-size:cover;--awb-box-shadow:5px 5px 10px 0px rgba(96,125,139,0.52);;--awb-border-radius:0px 0px 0px ;--awb-width-large:50%;--awb-margin-top-large:0px;--awb-spacing-right-large:calc( 0.1 * calc( 100% - 0px ) );--awb-margin-bottom-large:0px;--awb-spacing-left-large:calc( 0.1 * calc( 100% - 0px ) );--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:0px;--awb-spacing-left-medium:0px;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:0px;--awb-spacing-left-small:0px;\" data-animationType=\"fadeInLeft\" data-animationDuration=\"0.3\" data-animationOffset=\"top-into-view\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-center fusion-content-layout-column\"><div class=\"fusion-title title fusion-title-1 fusion-sep-none fusion-title-center fusion-title-text fusion-title-size-two\" style=\"--awb-text-color:#ffffff;--awb-margin-top-small:0px;--awb-margin-right-small:0px;--awb-margin-bottom-small:20px;--awb-margin-left-small:0px;\"><h2 class=\"fusion-title-heading title-heading-center fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:40;line-height:1.3;\">What is a vaccine response?<\/h2><\/div><div class=\"fusion-text fusion-text-2\"><p><span style=\"color: #ffffff;\">A vaccine response refers to the reaction of your immune system following vaccination. The\u00a0production of antibodies and immune cells called T cells are common features of a vaccine response and will be measured. These tests provide information on how someone has responded to the COVID-19 vaccines.\u00a0<\/span><\/p>\n<\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column_inner fusion-builder-nested-column-1 fusion_builder_column_inner_1_2 1_2 fusion-flex-column fusion-flex-align-self-center fusion-animated\" style=\"--awb-padding-right:3%;--awb-padding-bottom:3%;--awb-padding-left:3%;--awb-bg-color:#db3352;--awb-bg-color-hover:#db3352;--awb-bg-size:cover;--awb-box-shadow:5px 5px 10px 1px rgba(96,125,139,0.52);;--awb-width-large:50%;--awb-margin-top-large:0px;--awb-spacing-right-large:calc( 0.1 * calc( 100% - 0px ) );--awb-margin-bottom-large:0px;--awb-spacing-left-large:0px;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:0px;--awb-spacing-left-medium:0px;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:0px;--awb-spacing-left-small:0px;\" data-animationType=\"fadeInRight\" data-animationDuration=\"0.3\" data-animationOffset=\"top-into-view\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-center fusion-content-layout-column\"><div class=\"fusion-title title fusion-title-2 fusion-sep-none fusion-title-center fusion-title-text fusion-title-size-two\" style=\"--awb-text-color:#ffffff;--awb-margin-top-small:0px;--awb-margin-right-small:0px;--awb-margin-bottom-small:20px;--awb-margin-left-small:0px;\"><h2 class=\"fusion-title-heading title-heading-center fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:40;line-height:1.3;\"><div style=\"margin-top: 30px;\">What are antibodies?<\/div><\/h2><\/div><div class=\"fusion-text fusion-text-3\"><p><span style=\"color: #ffffff;\" data-contrast=\"auto\">Antibodies are substances that the body makes to protect people from infections like that caused by the virus responsible for COVID-19. <\/span><\/p>\n<p><span style=\"color: #ffffff;\">T cell responses can indicate how prepared the immune system is to fight off future infection with the COVID-19 virus. When an antibody test is positive, this indicates that there may have been previous vaccination or exposure to the COVID-19 virus and your body has built some protection against COVID-19.\u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-1 fusion_builder_column_1_2 1_2 fusion-flex-column\" style=\"--awb-padding-top:5%;--awb-padding-right:7%;--awb-padding-bottom:3%;--awb-padding-left:7%;--awb-padding-top-medium:60px;--awb-padding-bottom-medium:60px;--awb-bg-color:#db3352;--awb-bg-color-hover:#db3352;--awb-bg-size:cover;--awb-border-color:#e37222;--awb-border-top:0;--awb-border-right:0;--awb-border-bottom:0;--awb-border-left:0;--awb-border-style:solid;--awb-width-large:50%;--awb-margin-top-large:0px;--awb-spacing-right-large:0px;--awb-margin-bottom-large:0px;--awb-spacing-left-large:0px;--awb-width-medium:100%;--awb-spacing-right-medium:0px;--awb-spacing-left-medium:0px;--awb-width-small:100%;--awb-spacing-right-small:0px;--awb-spacing-left-small:0px;\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-title title fusion-title-3 fusion-sep-none fusion-title-text fusion-title-size-two\" style=\"--awb-text-color:#ffffff;--awb-margin-top-small:0px;--awb-margin-right-small:0px;--awb-margin-bottom-small:20px;--awb-margin-left-small:0px;\"><h2 class=\"fusion-title-heading title-heading-left fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:40;line-height:1.3;\">Who can participate in this study?<\/h2><\/div><div class=\"fusion-text fusion-text-4\"><p><span style=\"color: #ffffff;\">Anyone who identifies as being of Black Canadian ethnicity <\/span><\/p>\n<p><span style=\"color: #ffffff;\">Anyone who does not identify as Black Canadian can take part in the study in the comparison\/control group <\/span><\/p>\n<p><span style=\"color: #ffffff;\">Anyone eligible to receive a COVID-19 vaccine based on the most updated eligibility criteria in your province <\/span><\/p>\n<p><span style=\"color: #ffffff;\">Anyone planning to be or has already been vaccinated against COVID-19 <\/span><\/p>\n<p><span style=\"color: #ffffff;\">Anyone who is not currently sick from a COVID-19 infection and who resides in Ontario <\/span><\/p>\n<\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-2 fusion_builder_column_1_2 1_2 fusion-flex-column\" style=\"--awb-padding-top-medium:20vh;--awb-padding-bottom-medium:20vh;--awb-bg-position:center center;--awb-bg-size:cover;--awb-width-large:50%;--awb-margin-top-large:0px;--awb-spacing-right-large:0px;--awb-margin-bottom-large:0px;--awb-spacing-left-large:0px;--awb-width-medium:100%;--awb-spacing-right-medium:0px;--awb-spacing-left-medium:0px;--awb-width-small:100%;--awb-spacing-right-small:0px;--awb-spacing-left-small:0px;\"><div class=\"fusion-column-wrapper lazyload fusion-flex-justify-content-flex-start fusion-content-layout-column fusion-empty-column-bg-image fusion-column-has-bg-image\" data-bg-url=\"https:\/\/study.research.sickkids.ca\/wp-content\/uploads\/sites\/18\/2023\/02\/iStock-1030901680-3-1.jpg\" data-bg=\"https:\/\/study.research.sickkids.ca\/wp-content\/uploads\/sites\/18\/2023\/02\/iStock-1030901680-3-1.jpg\"><img decoding=\"async\" class=\"fusion-empty-dims-img-placeholder fusion-no-large-visibility\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\"><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-2 fusion-flex-container hundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:0px;--awb-padding-right:0px;--awb-padding-bottom:0px;--awb-padding-left:0px;--awb-background-color:#ffffff;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-stretch fusion-flex-content-wrap\" style=\"width:calc( 100% + 0px ) !important;max-width:calc( 100% + 0px ) !important;margin-left: calc(-0px \/ 2 );margin-right: calc(-0px \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-3 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-padding-top:3%;--awb-padding-right:3%;--awb-padding-bottom:3%;--awb-padding-left:3%;--awb-bg-color:rgba(255,255,255,0.3);--awb-bg-color-hover:rgba(255,255,255,0.3);--awb-bg-size:cover;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:0px;--awb-margin-bottom-large:0px;--awb-spacing-left-large:0px;--awb-width-medium:50%;--awb-spacing-right-medium:0px;--awb-spacing-left-medium:0px;--awb-width-small:100%;--awb-spacing-right-small:0px;--awb-spacing-left-small:0px;\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-separator fusion-full-width-sep\" style=\"align-self: center;margin-left: auto;margin-right: auto;margin-bottom:20px;width:100%;\"><\/div><div class=\"fusion-title title fusion-title-4 fusion-sep-none fusion-title-text fusion-title-size-two\" style=\"--awb-margin-top-small:0px;--awb-margin-right-small:0px;--awb-margin-bottom-small:20px;--awb-margin-left-small:0px;\"><h2 class=\"fusion-title-heading title-heading-left fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:40;line-height:1.5;\"><p style=\"text-align: left;\">What will happen in this study?<\/p><\/h2><\/div><div class=\"fusion-text fusion-text-5\"><p>During the study, you will have a minimum of one study visit, with additional visits following each vaccination dose over the duration of the study.<\/p>\n<p>A member of The Hospital for Sick Children (SickKids) team will visit you in the community close to where you live or will participate in a virtual visit with you from your area of residence. The first visit will include a blood test and a brief questionnaire.<\/p>\n<p>Once your blood sample is drawn, we will take the blood sample to SickKids or to another approved facility as appropriate for testing.<\/p>\n<\/div><div class=\"fusion-separator\" style=\"align-self: flex-start;margin-right:auto;flex-grow:1;margin-bottom:2%;width:100%;max-width:1000px;\"><div class=\"fusion-separator-border sep-single sep-dotted\" style=\"--awb-height:20px;--awb-amount:20px;--awb-sep-color:rgba(0,0,0,0.3);border-color:rgba(0,0,0,0.3);border-top-width:1px;\"><\/div><\/div><div class=\"fusion-title title fusion-title-5 fusion-sep-none fusion-title-text fusion-title-size-two\" style=\"--awb-margin-top-small:0px;--awb-margin-right-small:0px;--awb-margin-bottom-small:20px;--awb-margin-left-small:0px;\"><h2 class=\"fusion-title-heading title-heading-left fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:40;line-height:1.3;\">Where will the visits take place?<\/h2><\/div><div class=\"fusion-text fusion-text-6\"><p><span data-contrast=\"auto\">We will visit your community and will provide notice when and where we are coming.<\/span><span data-ccp-props=\"\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">This will be done through social media, posters, community leaders, churches, and other means.<\/span><span data-ccp-props=\"\">\u00a0<\/span><\/p>\n<\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-4 fusion_builder_column_1_1 1_1 fusion-flex-column fusion-flex-align-self-stretch\" style=\"--awb-padding-top:3%;--awb-padding-right:3%;--awb-padding-bottom:3%;--awb-padding-left:3%;--awb-bg-color:rgba(229,229,231,0.2);--awb-bg-color-hover:rgba(229,229,231,0.2);--awb-bg-size:cover;--awb-border-color:#de4561;--awb-border-style:solid;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:0px;--awb-margin-bottom-large:0px;--awb-spacing-left-large:0px;--awb-width-medium:100%;--awb-spacing-right-medium:0px;--awb-spacing-left-medium:0px;--awb-width-small:100%;--awb-spacing-right-small:0px;--awb-spacing-left-small:0px;\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-title title fusion-title-6 fusion-sep-none fusion-title-text fusion-title-size-two\" style=\"--awb-text-color:#de4561;--awb-margin-top-small:0px;--awb-margin-right-small:0px;--awb-margin-bottom-small:20px;--awb-margin-left-small:0px;--awb-font-size:35px;\"><h2 class=\"fusion-title-heading title-heading-left fusion-responsive-typography-calculated\" style=\"margin:0;letter-spacing:2px;font-size:1em;--fontSize:35;line-height:1.29;\"><div style=\"text-align: center;\"><span style=\"font-family: var(--h2_typography-font-family); font-size: 1em; font-style: var(--h2_typography-font-style,normal); font-weight: var(--h2_typography-font-weight);\">Are you interested in being a participant?<\/span><\/div><\/h2><\/div><div class=\"fusion-text fusion-text-7\"><p style=\"text-align: center;\" data-fusion-font=\"true\">To participate in the seroMARK-VR study, please fill out our contact form. After you submit the form, a member of the seroMARK project team will contact you to discuss next steps.<br \/>\n<span style=\"color: var(--body_typography-color); font-family: var(--body_typography-font-family); font-style: var(--body_typography-font-style,normal); font-weight: var(--body_typography-font-weight); letter-spacing: var(--body_typography-letter-spacing);\">By providing your contact information and submitting the form below, you are providing your consent to be contacted by the seroMARK project team at SickKids.<\/span><\/p>\n<\/div><div style=\"text-align:center;\"><a class=\"fusion-button button-flat fusion-button-default-size button-default fusion-button-default button-1 fusion-button-default-span fusion-button-default-type\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/redcapexternal.research.sickkids.ca\/surveys\/?s=WHDLHXXR7HFTWPYR\"><span class=\"fusion-button-text awb-button__text awb-button__text--default\">Vaccine Response participant contact form<\/span><\/a><\/div><\/div><\/div><\/div><\/div><\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":179,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"100-width.php","meta":{"footnotes":""},"class_list":["post-931","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - 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