What is the genMARK study?<\/h2>\n<\/div>Throughout the COVID-19 pandemic, a great variation in illness of individuals with COVID-19 has been noted. There are differences in both severity of the COVID-19 illness as well as the presentation of signs and symptoms. One reason for this variation could be our genetic differences that influence our body’s response to COVID-19 .<\/span><\/p>\nThe genMARK study focuses on children and adults with a spectrum of COVID-related illnesses. Using genetic research, this study seeks to understand whether a person’s genetics affect the severity of their COVID-19 illness.<\/p>\n<\/div>
The genMARK study aims to find out why some individuals have severe forms of Coronavirus (COVID-19) illness, while others get mild illness, even when they are otherwise healthy.<\/span><\/b><\/p>\n<\/div>Learn more<\/span><\/a><\/div><\/div><\/div><\/div>The genMARK study aims to find out why some individuals have severe forms of Coronavirus (COVID-19) illness, while others get mild illness, even when they are otherwise healthy.<\/span><\/b><\/p>\n<\/div><\/div>About the study<\/span><\/a><\/div><\/div><\/div><\/div><\/div>Study steering committee<\/h2>\n<\/div>The genMARK steering committee is made up of researchers who are most responsible for major decision-making for the research project. They work closely with other members of the research team, who collectively help to frame the conduct of the study, oversee deliverables and assist with knowledge translation.<\/p>\n<\/div><\/div><\/div>
![\"Dr.](\"https:\/\/study.research.sickkids.ca\/covidgenmark\/wp-content\/uploads\/sites\/19\/2020\/08\/UptonAllenP.png\")
<\/a><\/span><\/div><\/div><\/div>Dr. Upton Allen, <\/b>SickKids<\/span><\/p>\n<\/div><\/div><\/div>![\"Dr.](\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%27400%27%20height%3D%27500%27%20viewBox%3D%270%200%20400%20500%27%3E%3Crect%20width%3D%27400%27%20height%3D%27500%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\")
<\/a><\/span><\/div><\/div><\/div>Dr. Shaun Morris, <\/b>SickKids<\/span><\/span><\/p>\n<\/div><\/div><\/div><\/span><\/div><\/div><\/div>Dr. Julia Upton, <\/b>SickKids<\/span><\/span><\/p>\n<\/div><\/div><\/div>Collaborators<\/h2>\n<\/div><\/div><\/div>![\"Lisa](\"https:\/\/study.research.sickkids.ca\/covidgenmark\/wp-content\/uploads\/sites\/19\/2020\/08\/60812-Headshot_Lisa_Strug-p-1.png\")
<\/a><\/span><\/div><\/div><\/div>Dr. Lisa Strug, <\/b>SickKids, Liaison with HostSeq<\/span><\/span><\/p>\n<\/div><\/div><\/div>![\"Dr.](\"https:\/\/study.research.sickkids.ca\/covidgenmark\/wp-content\/uploads\/sites\/19\/2020\/08\/Jesse-PapenburgP.png\")
<\/a><\/span><\/div><\/div><\/div>Dr. Jesse Papenburg, <\/b>Montreal Children’s Hospital<\/span><\/span><\/p>\n<\/div><\/div><\/div>![\"Dr.](\"https:\/\/study.research.sickkids.ca\/covidgenmark\/wp-content\/uploads\/sites\/19\/2020\/08\/Manish-SadaranganiP.png\")
<\/a><\/span><\/div><\/div><\/div>Dr. Manish Sadarangani, <\/span><\/b>BC Children’s Hospital, IMPACT<\/span><\/span><\/p>\n<\/div><\/div><\/div>![\"Tex](\"https:\/\/study.research.sickkids.ca\/covidgenmark\/wp-content\/uploads\/sites\/19\/2023\/06\/image-600x750-1.png\")
<\/a><\/span><\/div><\/div><\/div>Dr. Tex Kissoon, <\/b>BC Children’s Hospital<\/span><\/span><\/p>\n<\/div><\/div><\/div>![\"Tex](\"https:\/\/study.research.sickkids.ca\/covidgenmark\/wp-content\/uploads\/sites\/19\/2023\/06\/image-600x750-2.png\")
<\/a><\/span><\/div><\/div><\/div>Dr. Hartley Garfield<\/span>, <\/b>Associate Professor, University of Toronto<\/span><\/span><\/p>\n<\/div><\/div><\/div>Not pictured:<\/span><\/p>\nDr. Allison McGeer, <\/b>Mount Sinai Hospital<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Collaborating sites<\/h2>\n<\/div>genMARK is an international study with collaborators from around the world.<\/p>\n<\/div>
<\/div>![\"\"](\"https:\/\/study.research.sickkids.ca\/wp-content\/uploads\/sites\/19\/2020\/08\/SK_PMS-300x90.png\")
<\/a>
\n![\"\"](\"https:\/\/study.research.sickkids.ca\/wp-content\/uploads\/sites\/19\/2020\/11\/SK-Foundation-Logo-150-300x148.png\")
<\/a>
\n![\"\"](\"https:\/\/study.research.sickkids.ca\/wp-content\/uploads\/sites\/19\/2020\/11\/University-of-Toronto-150-300x108.png\")
<\/a>
\n![\"\"](\"https:\/\/study.research.sickkids.ca\/wp-content\/uploads\/sites\/19\/2020\/11\/Cgen-150-300x130.png\")
<\/a><\/p>\n![\"\"](\"https:\/\/study.research.sickkids.ca\/wp-content\/uploads\/sites\/19\/2020\/11\/ISARIC_COVID-19_logo-150.png\")
<\/a>
\n![\"\"](\"https:\/\/study.research.sickkids.ca\/wp-content\/uploads\/sites\/19\/2020\/11\/St.-Michaels-Hospital-150.png\")
<\/a>
\n![\"\"](\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%27150%27%20height%3D%27126%27%20viewBox%3D%270%200%20150%20126%27%3E%3Crect%20width%3D%27150%27%20height%3D%27126%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\")
<\/a>
\n![\"\"](\"https:\/\/study.research.sickkids.ca\/wp-content\/uploads\/sites\/19\/2020\/11\/Montreal-Childrens-Hospital-150.png\")
<\/a><\/p>\nThe Centre for Applied Genomics<\/a><\/p>\nThe University of the West Indies<\/a><\/p>\nToronto Invasive Bacterial Diseases Network<\/a> (TIBDN)<\/span><\/p>\nMount Sinai Hospital<\/span><\/a><\/p>\nCanadian Immunization Monitoring Program, ACTive<\/a> (IMPACT)<\/span><\/p>\n<\/div>The Hospital for Sick Children (SickKids)<\/a><\/p>\nSickKids Foundation<\/a><\/p>\nThe Centre for Applied Genomics<\/a><\/p>\nCGEn<\/a><\/p>\nUniversity of Toronto<\/a><\/p>\nThe University of the West Indies<\/a><\/p>\nToronto Invasive Bacterial Diseases Network<\/a> (TIBDN)<\/p>\nBC Children\u2019s Hospital<\/a><\/p>\nMontreal Children\u2019s Hospital<\/a><\/p>\nMount Sinai Hospital<\/a><\/p>\nSt. Michael\u2019s Hospital<\/a><\/p>\nCanadian Immunization Monitoring Program, ACTive<\/a> (IMPACT)<\/p>\n
Throughout the COVID-19 pandemic, a great variation in illness of individuals with COVID-19 has been noted. There are differences in both severity of the COVID-19 illness as well as the presentation of signs and symptoms. One reason for this variation could be our genetic differences that influence our body’s response to COVID-19 .<\/span><\/p>\n The genMARK study focuses on children and adults with a spectrum of COVID-related illnesses. Using genetic research, this study seeks to understand whether a person’s genetics affect the severity of their COVID-19 illness.<\/p>\n<\/div> The genMARK study aims to find out why some individuals have severe forms of Coronavirus (COVID-19) illness, while others get mild illness, even when they are otherwise healthy.<\/span><\/b><\/p>\n<\/div> The genMARK study aims to find out why some individuals have severe forms of Coronavirus (COVID-19) illness, while others get mild illness, even when they are otherwise healthy.<\/span><\/b><\/p>\n<\/div> The genMARK steering committee is made up of researchers who are most responsible for major decision-making for the research project. They work closely with other members of the research team, who collectively help to frame the conduct of the study, oversee deliverables and assist with knowledge translation.<\/p>\n<\/div><\/div><\/div> Dr. Upton Allen, <\/b>SickKids<\/span><\/p>\n<\/div><\/div><\/div> Dr. Shaun Morris, <\/b>SickKids<\/span><\/span><\/p>\n<\/div><\/div><\/div> Dr. Julia Upton, <\/b>SickKids<\/span><\/span><\/p>\n<\/div><\/div><\/div> Dr. Lisa Strug, <\/b>SickKids, Liaison with HostSeq<\/span><\/span><\/p>\n<\/div><\/div><\/div> Dr. Jesse Papenburg, <\/b>Montreal Children’s Hospital<\/span><\/span><\/p>\n<\/div><\/div><\/div> Dr. Manish Sadarangani, <\/span><\/b>BC Children’s Hospital, IMPACT<\/span><\/span><\/p>\n<\/div><\/div><\/div> Dr. Tex Kissoon, <\/b>BC Children’s Hospital<\/span><\/span><\/p>\n<\/div><\/div><\/div> Dr. Hartley Garfield<\/span>, <\/b>Associate Professor, University of Toronto<\/span><\/span><\/p>\n<\/div><\/div><\/div> Not pictured:<\/span><\/p>\n Dr. Allison McGeer, <\/b>Mount Sinai Hospital<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div> genMARK is an international study with collaborators from around the world.<\/p>\n<\/div> The Centre for Applied Genomics<\/a><\/p>\n The University of the West Indies<\/a><\/p>\n Toronto Invasive Bacterial Diseases Network<\/a> (TIBDN)<\/span><\/p>\n Mount Sinai Hospital<\/span><\/a><\/p>\n Canadian Immunization Monitoring Program, ACTive<\/a> (IMPACT)<\/span><\/p>\n<\/div> The Hospital for Sick Children (SickKids)<\/a><\/p>\n SickKids Foundation<\/a><\/p>\n The Centre for Applied Genomics<\/a><\/p>\n CGEn<\/a><\/p>\n University of Toronto<\/a><\/p>\n The University of the West Indies<\/a><\/p>\n Toronto Invasive Bacterial Diseases Network<\/a> (TIBDN)<\/p>\n BC Children\u2019s Hospital<\/a><\/p>\n Montreal Children\u2019s Hospital<\/a><\/p>\n Mount Sinai Hospital<\/a><\/p>\n St. Michael\u2019s Hospital<\/a><\/p>\n Canadian Immunization Monitoring Program, ACTive<\/a> (IMPACT)<\/p>\nStudy steering committee<\/h2>\n<\/div>
<\/a><\/span><\/div>![\"Dr.](\"https:\/\/study.research.sickkids.ca\/wp-content\/uploads\/sites\/19\/2020\/08\/shaun-morris-p.png\")
![](\"https:\/\/study.research.sickkids.ca\/wp-content\/uploads\/sites\/19\/2020\/08\/Julia_Upton-p.png\")
Collaborators<\/h2>\n<\/div><\/div><\/div>
<\/a><\/span><\/div><\/a><\/span><\/div><\/a><\/span><\/div><\/a><\/span><\/div><\/a><\/span><\/div>Collaborating sites<\/h2>\n<\/div>
<\/a>
\n<\/a>
\n<\/a>
\n<\/a><\/p>\n<\/a>
\n<\/a>
\n![\"\"](\"https:\/\/study.research.sickkids.ca\/wp-content\/uploads\/sites\/19\/2020\/11\/BC-Childrens-Hospital-Logo-150.png\"){kind=logo}
\n<\/a><\/p>\n